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Synoviocyte innate responses: II. Pivotal role of interferon regulatory factor 3

INTRODUCTION: Innate immune responses likely contribute to synovial inflammation in rheumatoid arthritis (RA). Of the innate receptors implicated in RA, TLR3 activates several signaling cascades, including -interferon regulatory factors 3 and 7 (IRF), resulting in production of viral-stress IFN-indu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sweeney, Susan E., Kimbler, Trevor B., Firestein, Gary S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913682/
https://ncbi.nlm.nih.gov/pubmed/20483755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903944
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