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Ventral Tegmental Area BDNF Induces an Opiate-Dependent–Like Reward State in Naïve Rats
The neural mechanisms underlying the transition from a drug-nondependent to a drug-dependent state remain elusive. Chronic exposure to drugs has been shown to increase brain-derived neurotrophic factor (BDNF) levels in ventral tegmental area (VTA) neurons. BDNF infusions into the VTA potentiate seve...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2913611/ https://ncbi.nlm.nih.gov/pubmed/19478142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1168501 |
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