Ventral Tegmental Area BDNF Induces an Opiate-Dependent–Like Reward State in Naïve Rats

The neural mechanisms underlying the transition from a drug-nondependent to a drug-dependent state remain elusive. Chronic exposure to drugs has been shown to increase brain-derived neurotrophic factor (BDNF) levels in ventral tegmental area (VTA) neurons. BDNF infusions into the VTA potentiate seve...

Full description

Saved in:
Bibliographic Details
Main Authors: Vargas-Perez, Hector, Kee, Ryan Ting-A, Walton, Christine H., Hansen, D. Micah, Razavi, Rozita, Clarke, Laura, Bufalino, Mary Rose, Allison, David W., Steffensen, Scott C., van der Kooy, Derek
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913611/
https://ncbi.nlm.nih.gov/pubmed/19478142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1168501
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items