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Lesions of the Tegmental Pedunculopontine Nucleus Block the Rewarding Effects and Reveal the Aversive Effects of Nicotine in the Ventral Tegmental Area

Nicotine, the primary psychoactive component of tobacco smoke, is known to possess potent rewarding and aversive stimulus properties. The mammalian ventral tegmental area (VTA) is involved importantly in the mediation of the motivational effects of nicotine. However, the neural outputs from the VTA...

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Laviolette, Steven R., Alexson, Tania O., van der Kooy, Derek
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2002
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6757774/
https://ncbi.nlm.nih.gov/pubmed/12351739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-19-08653.2002
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