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Roles of Arginase variants, Atopy and Ozone in Childhood Asthma

BACKGROUND: Arginases (encoded by ARG1 and ARG2 genes) may play an important role in asthma pathogenesis through effects on nitrosative stress. Arginase expression is upregulated in asthma and varies with T helper type-2 cytokine levels and oxidative stress. OBJECTIVE: We aimed to examine whether va...

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Détails bibliographiques
Auteurs principaux: Salam, Muhammad T., Islam, Talat, Gauderman, W. James, Gilliland, Frank D
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913574/
https://ncbi.nlm.nih.gov/pubmed/19281908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2008.12.020
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