Microsomal epoxide hydrolase, glutathione S‐transferase P1, traffic and childhood asthma

BACKGROUND: Microsomal epoxide hydrolase (EPHX1) metabolises xenobiotics including polyaromatic hydrocarbons (PAHs). Functional variants at this locus have been associated with respiratory diseases. The effects of EPHX1 variants may depend upon exposures from tobacco smoke and traffic emissions that...

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Autori principali: Salam, Muhammad T, Lin, Pi‐Chu, Avol, Edward L, Gauderman, W James, Gilliland, Frank D
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Group 2007
Soggetti:
Asthma
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2094290/
https://ncbi.nlm.nih.gov/pubmed/17711870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thx.2007.080127
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