Microsomal epoxide hydrolase, glutathione S‐transferase P1, traffic and childhood asthma

BACKGROUND: Microsomal epoxide hydrolase (EPHX1) metabolises xenobiotics including polyaromatic hydrocarbons (PAHs). Functional variants at this locus have been associated with respiratory diseases. The effects of EPHX1 variants may depend upon exposures from tobacco smoke and traffic emissions that...

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Autors principals: Salam, Muhammad T, Lin, Pi‐Chu, Avol, Edward L, Gauderman, W James, Gilliland, Frank D
Format: Artigo
Idioma:Inglês
Publicat: BMJ Group 2007
Matèries:
Asthma
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2094290/
https://ncbi.nlm.nih.gov/pubmed/17711870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thx.2007.080127
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