Microsomal epoxide hydrolase, glutathione S‐transferase P1, traffic and childhood asthma

BACKGROUND: Microsomal epoxide hydrolase (EPHX1) metabolises xenobiotics including polyaromatic hydrocarbons (PAHs). Functional variants at this locus have been associated with respiratory diseases. The effects of EPHX1 variants may depend upon exposures from tobacco smoke and traffic emissions that...

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Main Authors: Salam, Muhammad T, Lin, Pi‐Chu, Avol, Edward L, Gauderman, W James, Gilliland, Frank D
Formato: Artigo
Idioma:Inglês
Publicado: BMJ Group 2007
Assuntos:
Asthma
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2094290/
https://ncbi.nlm.nih.gov/pubmed/17711870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thx.2007.080127
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