Transforming Growth Factor-β1 C-509T Polymorphism, Oxidant Stress, and Early-Onset Childhood Asthma

Rationale: Transforming growth factor (TGF)-β1 is involved in airway inflammation and remodeling, two key processes in asthma pathogenesis. Tobacco smoke and traffic emissions induce airway inflammation and modulate TGF-β1 gene expression. We hypothesized that the effects of functional TGF-β1 varian...

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Detalhes bibliográficos
Main Authors: Salam, Muhammad T., Gauderman, W. James, McConnell, Rob, Lin, Pi-Chu, Gilliland, Frank D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2007
Assuntos:
A. Asthma and Allergy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2176104/
https://ncbi.nlm.nih.gov/pubmed/17673695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200704-561OC
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