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The “Two faces” of Tumor Suppressor p53-revisited

About 15 years ago, several groups including ours had used matched pairs of cell lines carrying wild type or mutant p53 genes to ascertain a role for p53 in cell survival. These were isogenic cell lines differing only by p53 status. The trend at that time was to support p53-mediated apoptosis. Accor...

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Autori principali: Smith, Martin L., Kumar, M.A. Suresh
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913486/
https://ncbi.nlm.nih.gov/pubmed/20686673
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