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Mitochondrial and Plasma Membrane Citrate Transporters: Discovery of Selective Inhibitors and Application to Structure/Function Analysis

Cytoplasmic citrate is the prime carbon source for fatty acid, triacylglycerol, and cholesterol biosyntheses, and also regulates glucose metabolism via its allosteric inhibition of phosphofructokinase. It originates either via the efflux of citrate from the mitochondrial matrix on the inner membrane...

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Autores principales: Sun, Jiakang, Aluvila, Sreevidya, Kotaria, Rusudan, Mayor, June A., Walters, D. Eric, Kaplan, Ronald S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913483/
https://ncbi.nlm.nih.gov/pubmed/20686672
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