The Yeast Mitochondrial Citrate Transport Protein: Identification of the Lysine Residues Responsible for Inhibition Mediated by Pyridoxal 5′-Phosphate

The present investigation identifies the molecular basis for the well-documented inhibition of the mitochondrial inner membrane citrate transport protein (CTP) function by the lysine-selective reagent pyridoxal 5′-phosphate. Kinetic analysis indicates that PLP is a linear mixed inhibitor of the Cys-...

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Hlavní autoři: Remani, Sreevidya, Sun, Jiakang, Kotaria, Rusudan, Mayor, June A., Brownlee, June M., Harrison, David H. T., Walters, D. Eric, Kaplan, Ronald S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775541/
https://ncbi.nlm.nih.gov/pubmed/19002576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10863-008-9187-1
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