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The Yeast Mitochondrial Citrate Transport Protein: Identification of the Lysine Residues Responsible for Inhibition Mediated by Pyridoxal 5′-Phosphate
The present investigation identifies the molecular basis for the well-documented inhibition of the mitochondrial inner membrane citrate transport protein (CTP) function by the lysine-selective reagent pyridoxal 5′-phosphate. Kinetic analysis indicates that PLP is a linear mixed inhibitor of the Cys-...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2775541/ https://ncbi.nlm.nih.gov/pubmed/19002576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10863-008-9187-1 |
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