Conjugation of 2-(1′-Hexyloxyethyl)-2-devinylpyropheophorbide-a (HPPH) to Carbohydrates Changes its Subcellular Distribution and Enhances Photodynamic Activity in Vivo

The carbohydrate moieties on conjugating with 3-(1′-hexyloxyethyl)-3-devinyl pyropeophorbide-a (HPPH) altered the uptake and intracellular localization from mitochondria to lysosomes. In vitro, HPPH-Gal 9 PDT showed increased PDT efficacy over HPPH–PDT as detectable by the oxidative cross-linking of...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Zheng, Xiang, Morgan, Janet, Pandey, Suresh K., Chen, Yihui, Tracy, Erin, Baumann, Heinz, Missert, Joseph R., Batt, Carrie, Jackson, Jennifer, Bellnier, David A., Henderson, Barbara W., Pandey, Ravindra K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913405/
https://ncbi.nlm.nih.gov/pubmed/19507863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm9001617
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados