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Modulations of NeuroD Activity Contribute to the Differential Effects of Morphine and Fentanyl on Dendritic Spine Stability

The cellular level of neurogenic differentiation 1 (NeuroD) is modulated differentially by μ-opioid receptor agonists; fentanyl increases NeuroD level by reducing the amount of microRNA-190 (miR-190), an inhibitor of NeuroD expression, whereas morphine does not alter NeuroD level. In the current stu...

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Autors principals: Zheng, Hui, Zeng, Yan, Chu, Ji, Kam, Angel YuetFang, Loh, Horace H., Law, Ping-Yee
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913383/
https://ncbi.nlm.nih.gov/pubmed/20554861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6069-09.2010
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