The DNA Damage-Binding Protein XPC Is a Frequent Target for Inactivation in Squamous Cell Carcinomas

XPC, the main damage-recognition protein responsible for nucleotide excision repair of UVB damage to DNA, is lost or mutated in xeroderma pigmentosum group C (XP-C), a rare inherited disease characterized by high incidence and early onset of non-melanoma and melanoma skin cancers. The high incidence...

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Autores principales: de Feraudy, Sebastien, Ridd, Katie, Richards, Lauren M., Kwok, Pui-Yan, Revet, Ingrid, Oh, Dennis, Feeney, Luzviminda, Cleaver, James E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2010
Materias:
Short Communications
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913339/
https://ncbi.nlm.nih.gov/pubmed/20616346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090925
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