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p53 suppression overwhelms DNA polymerase η deficiency in determining the cellular UV DNA damage response
Xeroderma pigmentosum variant (XP-V) cells lack the damage-specific DNA polymerase η and have normal excision repair but show defective DNA replication after UV irradiation. Previous studies using cells transformed with SV40 or HPV16 (E6/E7) suggested that the S-phase response to UV damage is altere...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2239317/ https://ncbi.nlm.nih.gov/pubmed/17822965 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2007.07.005 |
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