Overexpression of Smad2 Drives House Dust Mite–mediated Airway Remodeling and Airway Hyperresponsiveness via Activin and IL-25

Rationale: Airway hyperreactivity and remodeling are characteristic features of asthma. Interactions between the airway epithelium and environmental allergens are believed to be important in driving development of pathology, particularly because altered epithelial gene expression is common in indivi...

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Main Authors: Gregory, Lisa G., Mathie, Sara A., Walker, Simone A., Pegorier, Sophie, Jones, Carla P., Lloyd, Clare M.
Formato: Artigo
Idioma:Inglês
Publicado: American Thoracic Society 2010
Assuntos:
A. Asthma and Allergy
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913231/
https://ncbi.nlm.nih.gov/pubmed/20339149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200905-0725OC
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