IL-25 drives remodelling in allergic airways disease induced by house dust mite

BACKGROUND: Overexpression of the transforming growth factor β family signalling molecule smad2 in the airway epithelium provokes enhanced allergen-induced airway remodelling in mice, concomitant with elevated levels of interleukin (IL)-25. OBJECTIVE: We investigated whether IL-25 plays an active ro...

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Detalhes bibliográficos
Main Authors: Gregory, Lisa G, Jones, Carla P, Walker, Simone A, Sawant, Devika, Gowers, Kate H C, Campbell, Gaynor A, McKenzie, Andrew N J, Lloyd, Clare M
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2013
Assuntos:
Respiratory Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534261/
https://ncbi.nlm.nih.gov/pubmed/23093652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thoraxjnl-2012-202003
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