Activatable Molecular Systems Using Homologous Near-Infrared Fluorescent Probes for Monitoring Enzyme Activities In Vitro, In Cellulo, and In Vivo

We have developed a generic approach to determine enzyme activities in vitro and monitor their functional status in vivo. Specifically, a method to generate donor (CbOH)-acceptor (Me(2)NCp) near infrared (NIR) fluorescent dye pairs for preparing enzyme activatable molecular systems were developed ba...

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Autori principali: Zhang, Zongren, Fan, Jinda, Cheney, Philip P., Berezin, Mikhail Y., Edwards, W. Barry, Akers, Walter J., Shen, Duanwen, Liang, Kexian, Culver, Joseph P., Achilefu, Samuel
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913166/
https://ncbi.nlm.nih.gov/pubmed/19718795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp800264k
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