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Lipid raft-dependent endocytosis: a new route for hepcidin-mediated regulation of ferroportin in macrophages
BACKGROUND: Expression of the iron exporter ferroportin at the plasma membrane of macrophages is enhanced by iron loading and is decreased by hepcidin. We previously showed that ferroportin is present in specific cell surface domains suggestive of lipid rafts. Herein, we have clarified the localizat...
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Huvudupphovsmän: | , , |
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Materialtyp: | Artigo |
Språk: | Inglês |
Publicerad: |
Ferrata Storti Foundation
2010
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Ämnen: | |
Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2913074/ https://ncbi.nlm.nih.gov/pubmed/20220061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.019992 |
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