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Hepcidin targets ferroportin for degradation in hepatocytes

Hepcidin, a circulating regulatory hormone peptide produced by hepatocytes, functions as the master regulator of cellular iron export by controlling the amount of ferroportin, an iron exporter present on the basolateral surface of intestinal enterocytes and macrophages. Hepcidin binding to ferroport...

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Autores principales: Ramey, Guillemette, Deschemin, Jean-Christophe, Durel, Béatrice, Canonne-Hergaux, François, Nicolas, Gaël, Vaulont, Sophie
Formato: Artigo
Lenguaje:Inglês
Publicado: Ferrata Storti Foundation 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833082/
https://ncbi.nlm.nih.gov/pubmed/19773263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.014399
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