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Hepcidin targets ferroportin for degradation in hepatocytes

Hepcidin, a circulating regulatory hormone peptide produced by hepatocytes, functions as the master regulator of cellular iron export by controlling the amount of ferroportin, an iron exporter present on the basolateral surface of intestinal enterocytes and macrophages. Hepcidin binding to ferroport...

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Autors principals: Ramey, Guillemette, Deschemin, Jean-Christophe, Durel, Béatrice, Canonne-Hergaux, François, Nicolas, Gaël, Vaulont, Sophie
Format: Artigo
Idioma:Inglês
Publicat: Ferrata Storti Foundation 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833082/
https://ncbi.nlm.nih.gov/pubmed/19773263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.014399
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