NF1 is a tumor suppressor in neuroblastoma that determines retinoic acid response and disease outcome

Retinoic acid (RA) induces differentiation of neuroblastoma cells in vitro and is used with variable success to treat aggressive forms of this disease. This variability in clinical response to RA is enigmatic, as no mutations in components of the RA signaling cascade have been found. Using a large-s...

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Detaylı Bibliyografya
Asıl Yazarlar: Hölzel, Michael, Huang, Sidong, Koster, Jan, Øra, Ingrid, Lakeman, Arjan, Caron, Huib, Nijkamp, Wouter, Xie, Jing, Callens, Tom, Asgharzadeh, Shahab, Seeger, Robert C., Messiaen, Ludwine, Versteeg, Rogier, Bernards, René
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913027/
https://ncbi.nlm.nih.gov/pubmed/20655465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.06.004
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