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Contributions of Selective Knockout Studies to Understanding Cholinesterase Disposition and Function

The complete knockout of the acetylcholinesterase gene (AChE) in the mouse yielded a surprising phenotype that could not have been predicted from deletion of the cholinesterase genes in Drosophila, that of a living, but functionally compromised animal. The phenotype of this animal showed a sufficien...

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Detalhes bibliográficos
Main Authors: Camp, Shelley, Zhang, Limin, Krejci, Eric, Dobbertin, Alexandre, Bernard, Véronique, Girard, Emmanuelle, Duysen, Ellen G., Lockridge, Oksana, De Jaco, Antonella, Taylor, Palmer
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912976/
https://ncbi.nlm.nih.gov/pubmed/20153304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2010.02.008
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