Targeting of Acetylcholinesterase in Neurons In Vivo: A Dual Processing Function for the Proline-Rich Membrane Anchor Subunit and the Attachment Domain on the Catalytic Subunit

Acetylcholinesterase (AChE) accumulates on axonal varicosities and is primarily found as tetramers associated with a proline-rich membrane anchor (PRiMA). PRiMA is a small transmembrane protein that efficiently transforms secreted AChE to an enzyme anchored on the outer cell surface. Surprisingly, i...

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Hauptverfasser: Dobbertin, Alexandre, Hrabovska, Anna, Dembele, Korami, Camp, Shelley, Taylor, Palmer, Krejci, Eric, Bernard, Véronique
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2009
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695489/
https://ncbi.nlm.nih.gov/pubmed/19357277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3863-08.2009
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