Targeting Acetylcholinesterase to Membrane Rafts: A FUNCTION MEDIATED BY THE PROLINE-RICH MEMBRANE ANCHOR (PRiMA) IN NEURONS

In the mammalian brain, acetylcholinesterase (AChE) is anchored in cell membranes by a transmembrane protein PRiMA (proline-rich membrane anchor). We present evidence that at least part of the PRiMA-linked AChE is integrated in membrane microdomains called rafts. A significant proportion of PRiMA-li...

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Détails bibliographiques
Auteurs principaux: Xie, Heidi Q., Liang, Dong, Leung, K. Wing, Chen, Vicky P., Zhu, Kevin Y., Chan, Wallace K. B., Choi, Roy C. Y., Massoulié, Jean, Tsim, Karl W. K.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2010
Sujets:
Membrane Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857032/
https://ncbi.nlm.nih.gov/pubmed/20147288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.038711
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