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EpCAM nuclear localization identifies aggressive Thyroid Cancer and is a marker for poor prognosis
BACKGROUND: Proteolytic cleavage of the extracellular domain (EpEx) of Epithelial cell adhesion molecule (EpCAM) and nuclear signaling by its intracellular oncogenic domain Ep-ICD has recently been implicated in increased proliferation of cancer cells. The clinical significance of Ep-ICD in human tu...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2912862/ https://ncbi.nlm.nih.gov/pubmed/20579375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-331 |
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