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Practical Considerations for Imputation of Untyped Markers in Admixed Populations

Imputation of genotypes for markers untyped in a study sample has become a standard approach to increase genome coverage in genome-wide association studies at practically zero cost. Most methods for imputing missing genotypes extend previously described algorithms for inferring haplotype phase. Thes...

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Hlavní autoři: Shriner, Daniel, Adeyemo, Adebowale, Chen, Guanjie, Rotimi, Charles N.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912698/
https://ncbi.nlm.nih.gov/pubmed/19918757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20457
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