The PB2-E627K Mutation Attenuates Viruses Containing the 2009 H1N1 Influenza Pandemic Polymerase

The swine-origin H1N1 influenza A virus emerged in early 2009 and caused the first influenza pandemic in 41 years. The virus has spread efficiently to both the Northern and the Southern Hemispheres and has been associated with over 16,000 deaths. Given the virus’s recent zoonotic origin, there is co...

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Detalhes bibliográficos
Main Authors: Jagger, Brett W., Memoli, Matthew J., Sheng, Zong-Mei, Qi, Li, Hrabal, Rachel J., Allen, Genevieve L., Dugan, Vivien G., Wang, Ruixue, Digard, Paul, Kash, John C., Taubenberger, Jeffery K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912665/
https://ncbi.nlm.nih.gov/pubmed/20689744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00067-10
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