An early ‘classical’ swine H1N1 influenza virus shows similar pathogenicity to the 1918 pandemic virus in ferrets and mice

The 1918 pandemic influenza virus has demonstrated significant pathogenicity in animal models and is the progenitor of ‘classical’ swine and modern seasonal human H1N1 lineages. Here we characterize the pathogenicity of an early ‘classical’ swine H1N1 influenza A virus isolated in 1931 compared to t...

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Bibliographic Details
Main Authors: Memoli, Matthew J., Tumpey, Terrence M., Jagger, Brett W., Dugan, Vivien G., Sheng, Zong-Mei, Qi, Li, Kash, John C., Taubenberger, Jeffery K.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763968/
https://ncbi.nlm.nih.gov/pubmed/19733889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.08.021
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