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A Data-Adaptive Sum Test for Disease Association with Multiple Common or Rare Variants
Since associations between complex diseases and common variants are typically weak, and approaches to genotyping rare variants (e.g. by next-generation resequencing) multiply, there is an urgent demand to develop powerful association tests that are able to detect disease associations with both commo...
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Main Authors: | , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
S. Karger AG
2010
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2912645/ https://ncbi.nlm.nih.gov/pubmed/20413981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000288704 |
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