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Temporal Constraints on the Incorporation of Regulatory Mutants in Evolutionary Pathways

Understanding the molecular details of the sequence of events in multistep evolutionary pathways can reveal the extent to which natural selection exploits regulatory mutations affecting expression, amino acid replacements affecting the active site, amino acid replacements affecting protein folding o...

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Hlavní autoři: Brown, Kyle M., DePristo, Mark A., Weinreich, Daniel M., Hartl, Daniel L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912465/
https://ncbi.nlm.nih.gov/pubmed/19602543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msp151
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