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Temporal Constraints on the Incorporation of Regulatory Mutants in Evolutionary Pathways

Understanding the molecular details of the sequence of events in multistep evolutionary pathways can reveal the extent to which natural selection exploits regulatory mutations affecting expression, amino acid replacements affecting the active site, amino acid replacements affecting protein folding o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Brown, Kyle M., DePristo, Mark A., Weinreich, Daniel M., Hartl, Daniel L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912465/
https://ncbi.nlm.nih.gov/pubmed/19602543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msp151
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