Site-specific introduction of an acetyl-lysine mimic into peptides and proteins by cysteine alkylation

[Image: see text] Protein acetylation on Lys residues is recognized as a significant post-translational modification in cells, but it is often difficult to discern the direct structural and functional effects of individual acetylation events. Here we describe a new tool, methylthiocarbonyl-aziridine...

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Autori principali: Huang, Rong, Holbert, Marc A., Tarrant, Mary Katherine, Curtet, Sandrine, Colquhoun, David R., Dancy, Beverley M., Dancy, Blair C., Hwang, Yousang, Tang, Yong, Meeth, Katrina, Marmorstein, Ronen, Cole, Robert N., Khochbin, Saadi, Cole, Philip A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912447/
https://ncbi.nlm.nih.gov/pubmed/20608637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja103954u
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