Site-specific introduction of an acetyl-lysine mimic into peptides and proteins by cysteine alkylation

[Image: see text] Protein acetylation on Lys residues is recognized as a significant post-translational modification in cells, but it is often difficult to discern the direct structural and functional effects of individual acetylation events. Here we describe a new tool, methylthiocarbonyl-aziridine...

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Bibliografiske detaljer
Main Authors: Huang, Rong, Holbert, Marc A., Tarrant, Mary Katherine, Curtet, Sandrine, Colquhoun, David R., Dancy, Beverley M., Dancy, Blair C., Hwang, Yousang, Tang, Yong, Meeth, Katrina, Marmorstein, Ronen, Cole, Robert N., Khochbin, Saadi, Cole, Philip A.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912447/
https://ncbi.nlm.nih.gov/pubmed/20608637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja103954u
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