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Thymidylate Synthase Catalyzed H-transfers: Two Chapters in One Tale

Examination of the nature of different bond-activations along the same catalytic path is of general interest in chemistry and biology. In this report we compare the physical nature of two sequential H-transfers in the same enzymatic reaction. Thymidylate synthase (TSase) catalyzes a complex reaction...

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Detalhes bibliográficos
Main Authors: Wang, Zhen, Kohen, Amnon
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912445/
https://ncbi.nlm.nih.gov/pubmed/20575541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja103010b
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