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A Stereoelectronic Effect in Prebiotic Nucleotide Synthesis

A plausible route for the spontaneous synthesis of an activated ribonucleotide that is poised for polymerization has been put forth (Powner et al., Nature 2009f, 459, 239–242). A key step in this route necessitates the regioselective phosphorylation of the secondary alcohol on C(3′), of an anhydroar...

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Detalhes bibliográficos
Main Authors: Choudhary, Amit, Kamer, Kimberli J., Powner, Matthew W., Sutherland, John D., Raines, Ronald T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912435/
https://ncbi.nlm.nih.gov/pubmed/20499895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb100093g
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