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Specificity and Membrane Partitioning of Grsp1 Signaling Complexes with Grp1 Family ARF Exchange Factors
The Arf exchange factor Grp1 selectively binds phosphatidylinositol 3,4,5-triphosphate (PtdIns(3,4,5)P(3)), which is required for recruitment to the plasma membrane in stimulated cells. The mechanisms for phosphoinositide recognition by the PH domain, catalysis of nucleotide exchange by the Sec7 dom...
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| Glavni autori: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2912425/ https://ncbi.nlm.nih.gov/pubmed/20527794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1000454 |
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