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Selective 2′-Hydroxyl Acylation Analyzed by Protection from Exoribonuclease

[Image: see text] Selective 2′-hydroxyl acylation analyzed by primer extension (SHAPE) is a powerful approach for characterizing RNA structure and dynamics at single-nucleotide resolution. However, SHAPE technology is limited, sometimes severely, because primer extension detection obscures structura...

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Détails bibliographiques
Auteurs principaux: Steen, Kady-Ann, Malhotra, Arun, Weeks, Kevin M.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912424/
https://ncbi.nlm.nih.gov/pubmed/20597503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja103781u
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