A carregar...
FULLY SUBSTITUTED CARBON CENTERS BY DIASTEREOSELECTIVE SPIROCYCLIZATION: STEREOSELECTIVE SYNTHESIS OF (+)-LEPADIFORMINE C
Reductive lithiation of N-Boc α-amino nitriles generated α-amino alkyllithium reagents with unexpected selectivity. The intermediate radical prefers to align with the nitrogen lone pair, and this interaction leads to an A(1,3)-strain effect that biases the conformation of the radical. In cyclohexane...
Na minha lista:
| Main Authors: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2912418/ https://ncbi.nlm.nih.gov/pubmed/20578697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja104250b |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|