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Diastereoselective Synthesis of the Pectenotoxin 2 Non-Anomeric AB Spiroacetal

The reductive cyclization reaction of a cyanoacetal has been used to prepare the pectenotoxin 2 (PTX-2) AB spiroacetal with high diastereoselectively for the first time. The strategy is convergent and makes use of the axial-selective reductive lithiation of 2-cyano tetrahydropyran rings to introduce...

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Detaylı Bibliyografya
Asıl Yazarlar: Vellucci, Danielle, Rychnovsky, Scott D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2487677/
https://ncbi.nlm.nih.gov/pubmed/17286378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol0630447
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