The heparan sulfate co-receptor and the concentration of fibroblast growth factor-2 independently elicit different signalling patterns from the fibroblast growth factor receptor

BACKGROUND: The fibroblast growth factor receptor (FGFR) interprets concentration gradients of FGF ligands and structural changes in the heparan sulfate (HS) co-receptor to generate different cellular responses. However, whether the FGFR generates different signals is not known. RESULTS: We have pre...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Zhu, Hongyan, Duchesne, Laurence, Rudland, Philip S, Fernig, David G
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912315/
https://ncbi.nlm.nih.gov/pubmed/20576134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-8-14
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares