ROS accumulation and IGF-IR inhibition contribute to fenofibrate/PPARα -mediated inhibition of Glioma cell motility in vitro

BACKGROUND: Glioblastomas are characterized by rapid cell growth, aggressive CNS infiltration, and are resistant to all known anticancer regimens. Recent studies indicate that fibrates and statins possess anticancer potential. Fenofibrate is a potent agonist of peroxisome proliferator activated rece...

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Autors principals: Drukala, Justyna, Urbanska, Katarzyna, Wilk, Anna, Grabacka, Maja, Wybieralska, Ewa, Del Valle, Luis, Madeja, Zbigniew, Reiss, Krzysztof
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912247/
https://ncbi.nlm.nih.gov/pubmed/20569465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-159
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