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Structural Characterization of Mutations at the Oxygen Activation Site in Monomeric Sarcosine Oxidase
Oxygen reduction and sarcosine oxidation in monomeric sarcosine oxidase (MSOX) occur at separate sites above the si- and re-face, respectively, of the flavin ring. Mutagenesis studies implicate Lys265 as the oxygen activation site. Substitution of Lys265 by a neutral (Met, Gln, Ala) or basic (Arg) r...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2912214/ https://ncbi.nlm.nih.gov/pubmed/20353187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100160j |
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