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Hypoxia-inducible factor 2α regulates macrophage function in mouse models of acute and tumor inflammation
Hypoxia-inducible factor 1α (HIF-1α) and HIF-2α display unique and sometimes opposing activities in regulating cellular energy homeostasis, cell fate decisions, and oncogenesis. Macrophages exposed to hypoxia accumulate both HIF-1α and HIF-2α, and overexpression of HIF-2α in tumor-associated macroph...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Clinical Investigation
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2912179/ https://ncbi.nlm.nih.gov/pubmed/20644254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI39506 |
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