Organ-Specific Roles of CYP1A1 during Detoxication of Dietary Benzo[a]pyrene

Polycyclic aromatic hydrocarbons (PAHs) are widely distributed environmental toxicants derived from sources that include cigarette smoke, petroleum distillation, gas- and diesel-engine exhaust, and charcoal-grilled food. The gastrointestinal tract is the principal route of PAH exposures, even when i...

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Hlavní autoři: Shi, Zhanquan, Dragin, Nadine, Gálvez-Peralta, Marina, Jorge-Nebert, Lucia F., Miller, Marian L., Wang, Bin, Nebert, Daniel W.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912055/
https://ncbi.nlm.nih.gov/pubmed/20371670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.063438
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