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Vitamin K Prevents Oxidative Cell Death by Inhibiting Activation of 12-Lipoxygenase in Developing Oligodendrocytes

Oxidative mechanisms of injury are important in many neurological disorders. Developing oligodendrocytes (pre-OLs) are particularly sensitive to oxidative stress-mediated injury. We previously demonstrated a novel function of phylloquinone (vitamin K(1)) and menaquinone 4 (MK-4; a major form of vita...

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Detalhes bibliográficos
Main Authors: Li, Jianrong, Wang, Hong, Rosenberg, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911960/
https://ncbi.nlm.nih.gov/pubmed/19235890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22029
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