Peroxynitrite-Induced Neuronal Apoptosis Is Mediated by Intracellular Zinc Release and 12-Lipoxygenase Activation

Peroxynitrite toxicity is a major cause of neuronal injury in stroke and neurodegenerative disorders. The mechanisms underlying the neurotoxicity induced by peroxynitrite are still unclear. In this study, we observed that TPEN [N,N,N′,N′-tetrakis (2-pyridylmethyl)ethylenediamine], a zinc chelator, p...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Zhang, Yumin, Wang, Hong, Li, Jianrong, Jimenez, Daniel A., Levitan, Edwin S., Aizenman, Elias, Rosenberg, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Cellular/Molecular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945223/
https://ncbi.nlm.nih.gov/pubmed/15564577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2469-04.2004
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados