Peptidyl arginine deiminase type IV (PADI4) haplotypes interact with shared epitope regardless of anti-cyclic citrullinated peptide antibody or erosive joint status in rheumatoid arthritis: a case control study

INTRODUCTION: Anti-cyclic citrullinated peptide autoantibodies (anti-CCP) are the most specific serologic marker for rheumatoid arthritis (RA). Genetic polymorphisms in a citrullinating (or deiminating) enzyme, peptidyl arginine deiminase type IV (PADI4) have been reproducibly associated with RA sus...

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Main Authors: Bang, So-Young, Han, Tae-Un, Choi, Chan-Bum, Sung, Yoon-Kyoung, Bae, Sang-Cheol, Kang, Changwon
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911908/
https://ncbi.nlm.nih.gov/pubmed/20537173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3051
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