Release of Active Peptidyl Arginine Deiminases by Neutrophils Can Explain Production of Extracellular Citrullinated Autoantigens in Rheumatoid Arthritis Synovial Fluid

OBJECTIVE: In the majority of patients with rheumatoid arthritis (RA), antibodies specifically recognize citrullinated autoantigens that are generated by peptidylarginine deiminases (PADs). Neutrophils express high levels of PAD and accumulate in the synovial fluid (SF) of RA patients during disease...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Arthritis Rheumatol
Egile Nagusiak: Spengler, Julia, Lugonja, Božo, Jimmy Ytterberg, A., Zubarev, Roman A., Creese, Andrew J., Pearson, Mark J., Grant, Melissa M., Milward, Michael, Lundberg, Karin, Buckley, Christopher D., Filer, Andrew, Raza, Karim, Cooper, Paul R., Chapple, Iain L., Scheel‐Toellner, Dagmar
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2015
Gaiak:
Rheumatoid Arthritis
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832324/
https://ncbi.nlm.nih.gov/pubmed/26245941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39313
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