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Autocitrullination of human peptidyl arginine deiminase type 4 regulates protein citrullination during cell activation

OBJECTIVE: To address mechanisms that control the activity of human peptidyl arginine deiminase type 4 (PAD-4). METHODS: PAD-4 autocitrullination was determined by anti–modified citrulline immunoblotting, using purified recombinant and endogenous PAD-4 from activated human primary neutrophils and ce...

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Detalhes bibliográficos
Main Authors: Andrade, Felipe, Darrah, Erika, Gucek, Marjan, Cole, Robert N., Rosen, Antony, Zhu, Xiaoming
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951335/
https://ncbi.nlm.nih.gov/pubmed/20201080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27439
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