Obesity affects the chondrocyte responsiveness to leptin in patients with osteoarthritis

INTRODUCTION: Increasing evidence support the regulatory role of leptin in osteoarthritis (OA). As high circulating concentrations of leptin disrupt the physiological function of the adipokine in obese individuals, the current study has been undertaken to determine whether the elevated levels of lep...

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Bibliographic Details
Main Authors: Pallu, Stéphane, Francin, Pierre-Jean, Guillaume, Cécile, Gegout-Pottie, Pascale, Netter, Patrick, Mainard, Didier, Terlain, Bernard, Presle, Nathalie
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911905/
https://ncbi.nlm.nih.gov/pubmed/20534145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3048
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